Insider Trading activities at Crispr Therapeutics Ag (CRSP)

Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Crispr Therapeutics Ag (CRSP) since 2016 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Crispr Therapeutics Ag. Table 2 shows the detailed insider transactions. This company's CIK number is 1674416.

Total stock buying since 2016: $293,942,208.
Total stock sales since 2016: $373,417,799.
Total stock option exercises since 2016: $19,239,965.

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Table 1. Yearly summary of insider stock purchases, sales, and option exercises at *Crispr Therapeutics Ag* (*CRSP*).
	Insider Buying		Insider Sales		Option Exercises
Year	Shares	Value	Shares	Value	Shares	Value
2025	4,976,060	$258,954,140	124,854	$6,280,789	157,497	$0
2024	0	$0	213,469	$13,804,447	210,103	$2,477,607
2023	0	$0	125,000	$6,506,300	178,754	$2,390,000
2022	0	$0	150,000	$9,148,625	292,152	$2,545,901
2021	0	$0	398,877	$62,188,865	382,267	$2,802,515
2020	0	$0	963,688	$100,088,841	493,985	$6,475,496
2019	0	$0	459,118	$21,805,542	141,618	$778,761
2018	724,346	$16,626,368	2,353,910	$113,098,938	185,500	$1,065,394
2017	0	$0	2,185,156	$40,495,452	285,421	$704,291
2016	1,311,550	$18,361,700	0	$0	0	$0

Table 2. Monthly summary of insider trading at *Crispr Therapeutics Ag* (*CRSP*).
Trading Period	Insider Buying		Insider Sales		Option Exercises
year-month	Shares	Value	Shares	Value	Shares	Value
2025-08	20,000	$1,140,600	13,081	$760,660	25,000	$0
2025-07	4,949,060	$257,499,590	0	$0	0	$0
2025-05	0	$0	3,932	$141,316	10,000	$0
2025-03	0	$0	40,678	$1,708,034	84,772	$0
2025-02	7,000	$313,950	67,163	$3,670,779	37,725	$0
2024-12	0	$0	15,000	$826,560	0	$0
2024-11	0	$0	30,000	$1,675,500	0	$0
2024-10	0	$0	5,382	$249,078	10,446	$0
2024-06	0	$0	3,366	$188,798	7,000	$0
2024-04	0	$0	19,582	$1,177,681	19,582	$374,407
2024-03	0	$0	41,856	$3,119,235	66,000	$382,400
2024-02	0	$0	28,283	$2,277,485	37,075	$382,400
2024-01	0	$0	70,000	$4,290,110	70,000	$1,338,400
2023-05	0	$0	25,000	$1,628,350	31,938	$478,000
2023-04	0	$0	25,000	$1,274,350	25,000	$478,000
2023-03	0	$0	25,000	$1,114,475	50,916	$478,000
2023-02	0	$0	25,000	$1,212,350	45,900	$478,000
2023-01	0	$0	25,000	$1,276,775	25,000	$478,000
2022-12	0	$0	25,000	$1,028,350	129,900	$583,401
2022-11	0	$0	25,000	$1,365,275	25,000	$478,000
2022-10	0	$0	0	$0	3,750	$0
2022-09	0	$0	25,000	$1,619,350	25,000	$405,250
2022-08	0	$0	25,000	$1,672,975	25,000	$405,250
2022-07	0	$0	25,000	$1,915,850	25,000	$359,750

Table 3. Detailed insider trading at *Crispr Therapeutics Ag* (*CRSP*)
Trade Date	Insider Name	Trade Type	Shares	Price ($)	Value ($)
2025-08-18	Kulkarni Samarth (Chief Executive Officer)	Sale	13,081	58.15	760,660
2025-08-16	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	.00	0
2025-08-06	Treco Douglas A	Buy	20,000	57.03	1,140,600
2025-07-16	George Simeon	Buy	2,969,436	52.03	154,499,754
2025-05-29	Patel Naimish (Chief Medical Officer)	Sale	3,932	35.94	141,316
2025-05-28	Patel Naimish (Chief Medical Officer)	Option Ex	10,000	.00	0
2025-03-21	Bruno Julianne (Chief Operating Officer)	Sale	1,714	41.23	70,668
2025-03-21	Prasad Raju (Chief Financial Officer)	Sale	2,197	41.23	90,582
2025-03-21	Kasinger James R. (General Counsel and Secretary)	Sale	3,185	41.23	131,317
2025-03-21	Kulkarni Samarth (Chief Executive Officer)	Sale	10,031	41.23	413,578
2025-03-20	Bruno Julianne (Chief Operating Officer)	Option Ex	3,750	.00	0
2025-03-20	Prasad Raju (Chief Financial Officer)	Option Ex	6,250	.00	0
2025-03-20	Kasinger James R. (General Counsel and Secretary)	Option Ex	6,250	.00	0
2025-03-20	Kulkarni Samarth (Chief Executive Officer)	Option Ex	19,688	.00	0
2025-03-17	Prasad Raju (Chief Financial Officer)	Sale	3,762	41.80	157,251
2025-03-14	Prasad Raju (Chief Financial Officer)	Option Ex	10,000	.00	0
2025-03-12	Bruno Julianne (Chief Operating Officer)	Sale	190	43.32	8,230
2025-03-12	Kasinger James R. (General Counsel and Secretary)	Sale	1,116	43.32	48,345
2025-03-12	Kulkarni Samarth (Chief Executive Officer)	Sale	4,462	43.32	193,293
2025-03-11	Bruno Julianne (Chief Operating Officer)	Sale	1,198	42.42	50,819
2025-03-11	Bruno Julianne (Chief Operating Officer)	Option Ex	435	.00	0
2025-03-11	Kasinger James R. (General Counsel and Secretary)	Sale	2,850	42.42	120,897
2025-03-11	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,250	.00	0
2025-03-11	Kulkarni Samarth (Chief Executive Officer)	Sale	9,973	42.42	423,054
2025-03-11	Kulkarni Samarth (Chief Executive Officer)	Option Ex	9,000	.00	0
2025-03-10	Bruno Julianne (Chief Operating Officer)	Option Ex	2,399	.00	0
2025-03-10	Kasinger James R. (General Counsel and Secretary)	Option Ex	5,500	.00	0
2025-03-10	Kulkarni Samarth (Chief Executive Officer)	Option Ex	19,250	.00	0
2025-02-26	Greene John	Buy	7,000	44.85	313,950
2025-02-19	Bruno Julianne (Chief Operating Officer)	Sale	333	52.80	17,582
2025-02-19	Kasinger James R. (General Counsel and Secretary)	Sale	1,947	52.80	102,801
2025-02-19	Kulkarni Samarth (Chief Executive Officer)	Sale	25,288	54.00	1,379,361
2025-02-18	Bruno Julianne (Chief Operating Officer)	Option Ex	650	.00	0
2025-02-18	Kasinger James R. (General Counsel and Secretary)	Sale	9,595	53.85	516,690
2025-02-18	Kasinger James R. (General Counsel and Secretary)	Option Ex	3,825	.00	0
2025-02-18	Kulkarni Samarth (Chief Executive Officer)	Sale	11,640	55.05	640,782
2025-02-18	Kulkarni Samarth (Chief Executive Officer)	Option Ex	13,250	.00	0
2025-02-16	Kasinger James R. (General Counsel and Secretary)	Option Ex	20,000	.00	0
2024-12-02	Kulkarni Samarth (Chief Executive Officer)	Sale	15,000	55.10	826,560
2024-11-11	Kulkarni Samarth (Chief Executive Officer)	Sale	30,000	55.85	1,675,500
2024-10-14	Kasinger James R. (General Counsel and Secretary)	Sale	1,089	46.28	50,398
2024-10-14	Kulkarni Samarth (Chief Executive Officer)	Sale	4,293	46.28	198,680
2024-10-13	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,113	.00	0
2024-10-13	Kulkarni Samarth (Chief Executive Officer)	Option Ex	8,333	.00	0
2024-06-21	Bruno Julianne (Chief Operating Officer)	Sale	3,366	56.09	188,798
2024-06-20	Bruno Julianne (Chief Operating Officer)	Option Ex	7,000	.00	0
2024-04-15	Kulkarni Samarth (Chief Executive Officer)	Sale	19,582	60.14	1,177,681
2024-04-15	Kulkarni Samarth (Chief Executive Officer)	Option Ex	19,582	19.12	374,407
2024-03-15	Prasad Raju (Chief Financial Officer)	Sale	3,524	72.69	256,159
2024-03-15	Kulkarni Samarth (Chief Executive Officer)	Sale	20,000	72.52	1,450,300
2024-03-15	Kulkarni Samarth (Chief Executive Officer)	Option Ex	20,000	19.12	382,400
2024-03-14	Prasad Raju (Chief Financial Officer)	Option Ex	10,000	.00	0
2024-03-12	Kasinger James R. (General Counsel and Secretary)	Sale	1,146	74.44	85,308
2024-03-12	Kulkarni Samarth (Chief Executive Officer)	Sale	4,583	74.44	341,158
2024-03-11	Kasinger James R. (General Counsel and Secretary)	Sale	2,801	78.26	219,206
2024-03-11	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,250	.00	0
2024-03-11	Kulkarni Samarth (Chief Executive Officer)	Sale	9,802	78.26	767,104
2024-03-11	Kulkarni Samarth (Chief Executive Officer)	Option Ex	9,000	.00	0
2024-03-10	Kasinger James R. (General Counsel and Secretary)	Option Ex	5,500	.00	0
2024-03-10	Kulkarni Samarth (Chief Executive Officer)	Option Ex	19,250	.00	0
2024-02-20	Kasinger James R. (General Counsel and Secretary)	Sale	1,913	79.67	152,408
2024-02-20	Kulkarni Samarth (Chief Executive Officer)	Sale	6,370	79.67	507,497
2024-02-18	Kasinger James R. (General Counsel and Secretary)	Option Ex	3,825	.00	0
2024-02-18	Kulkarni Samarth (Chief Executive Officer)	Option Ex	13,250	.00	0
2024-02-15	Kulkarni Samarth (Chief Executive Officer)	Sale	20,000	80.88	1,617,580
2024-02-15	Kulkarni Samarth (Chief Executive Officer)	Option Ex	20,000	19.12	382,400
2024-01-29	Kulkarni Samarth (Chief Executive Officer)	Sale	50,000	60.80	3,040,050
2024-01-29	Kulkarni Samarth (Chief Executive Officer)	Option Ex	50,000	19.12	956,000
2024-01-16	Kulkarni Samarth (Chief Executive Officer)	Sale	20,000	62.50	1,250,060
2024-01-16	Kulkarni Samarth (Chief Executive Officer)	Option Ex	20,000	19.12	382,400
2023-05-30	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	65.13	1,628,350
2023-05-30	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2023-05-23	Morrow Phuong Khanh (Chief Medical Officer)	Option Ex	6,938	.00	0
2023-04-25	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	50.97	1,274,350
2023-04-25	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2023-03-29	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	44.58	1,114,475
2023-03-29	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2023-03-11	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,250	.00	0
2023-03-11	Kulkarni Samarth (Chief Executive Officer)	Option Ex	9,000	.00	0
2023-03-10	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,833	.00	0
2023-03-10	Kulkarni Samarth (Chief Executive Officer)	Option Ex	11,833	.00	0
2023-02-27	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	48.49	1,212,350
2023-02-27	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2023-02-18	Smith Brendan (Chief Financial Officer)	Option Ex	3,825	.00	0
2023-02-18	Kasinger James R. (General Counsel and Secretary)	Option Ex	3,825	.00	0
2023-02-18	Kulkarni Samarth (Chief Executive Officer)	Option Ex	13,250	.00	0
2023-01-27	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	51.07	1,276,775
2023-01-27	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2022-12-28	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	41.13	1,028,350
2022-12-28	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2022-12-06	Kulkarni Samarth (Chief Executive Officer)	Option Ex	58,233	1.81	105,401
2022-12-03	Kasinger James R. (General Counsel and Secretary)	Option Ex	6,667	.00	0
2022-12-03	Kulkarni Samarth (Chief Executive Officer)	Option Ex	40,000	.00	0
2022-11-28	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	54.61	1,365,275
2022-11-28	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	19.12	478,000
2022-10-14	Smith Brendan (Chief Financial Officer)	Option Ex	3,750	.00	0
2022-09-28	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	64.77	1,619,350
2022-09-28	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	16.21	405,250
2022-08-29	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	66.92	1,672,975
2022-08-29	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	16.21	405,250
2022-07-27	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	76.63	1,915,850
2022-07-27	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	14.39	359,750
2022-06-29	Kulkarni Samarth (Chief Executive Officer)	Sale	25,000	61.87	1,546,825
2022-06-29	Kulkarni Samarth (Chief Executive Officer)	Option Ex	25,000	12.57	314,250
2022-03-11	Klein Lawrence Otto (CBO & COO)	Option Ex	3,000	.00	0
2022-03-11	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,250	.00	0
2022-03-11	Kulkarni Samarth (Chief Executive Officer)	Option Ex	9,000	.00	0
2022-03-10	Klein Lawrence Otto (CBO & COO)	Option Ex	4,584	.00	0
2022-03-10	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,834	.00	0
2022-03-10	Kulkarni Samarth (Chief Executive Officer)	Option Ex	11,834	.00	0
2021-12-20	Kulkarni Samarth (Chief Executive Officer)	Option Ex	17,750	1.81	32,127
2021-12-03	Klein Lawrence Otto (CBO & COO)	Option Ex	26,667	.00	0
2021-12-03	Ho Tony W (Executive VP, Head of R&D)	Option Ex	26,667	.00	0
2021-12-03	Kasinger James R. (General Counsel and Secretary)	Option Ex	13,333	.00	0
2021-12-03	Kulkarni Samarth (Chief Executive Officer)	Option Ex	80,000	.00	0
2021-12-02	Kasinger James R. (General Counsel and Secretary)	Option Ex	7,342	13.62	99,998
2021-10-15	Kulkarni Samarth (Chief Executive Officer)	Option Ex	33,000	1.81	59,730
2021-09-10	Klein Lawrence Otto (CBO & COO)	Option Ex	10,000	.00	0
2021-09-10	Kasinger James R. (General Counsel and Secretary)	Option Ex	10,000	.00	0
2021-08-06	Tomsicek Michael John (Chief Financial Officer)	Sale	25,000	138.84	3,471,000
2021-08-06	Tomsicek Michael John (Chief Financial Officer)	Option Ex	25,000	17.75	443,750
2021-08-05	Kulkarni Samarth (Chief Executive Officer)	Sale	28,500	128.73	3,668,919
2021-08-05	Kulkarni Samarth (Chief Executive Officer)	Option Ex	28,500	12.57	358,245
2021-08-04	Kulkarni Samarth (Chief Executive Officer)	Sale	1,500	125.02	187,530
2021-08-04	Kulkarni Samarth (Chief Executive Officer)	Option Ex	1,500	12.57	18,855
2021-07-19	Bolzon Bradley J Phd (Director)	Sale	10,000	127.03	1,270,340
2021-06-30	Novak Rodger (President)	Sale	25,000	165.00	4,125,000
2021-06-21	Novak Rodger (President)	Sale	25,000	128.07	3,201,675
2021-06-11	Bolzon Bradley J Phd (Director)	Sale	10,000	127.64	1,276,400
2021-03-22	Bolzon Bradley J Phd (Director)	Sale	30,374	132.28	4,017,963
2021-03-10	Klein Lawrence Otto (CBO & COO)	Option Ex	4,583	.00	0
2021-03-10	Ho Tony W (Executive VP, Head of R&D)	Option Ex	4,583	.00	0
2021-03-10	Kasinger James R. (General Counsel and Secretary)	Option Ex	2,833	.00	0
2021-03-10	Kulkarni Samarth (Chief Executive Officer)	Option Ex	11,833	.00	0
2021-03-10	Tomsicek Michael John (Chief Financial Officer)	Option Ex	2,833	.00	0
2021-03-05	Ho Tony W (Executive VP, Head of R&D)	Option Ex	3,333	.00	0
2021-02-19	Bolzon Bradley J Phd (Director)	Sale	171,003	149.99	25,648,568
2021-01-19	Kasinger James R. (General Counsel and Secretary)	Sale	27,500	205.45	5,649,820
2021-01-19	Kasinger James R. (General Counsel and Secretary)	Option Ex	27,500	51.49	1,415,975
2021-01-15	Klein Lawrence Otto (CBO & COO)	Sale	25,000	215.28	5,381,950
2021-01-15	Klein Lawrence Otto (CBO & COO)	Option Ex	25,010	13.50	337,635
2021-01-15	Kulkarni Samarth (Chief Executive Officer)	Sale	20,000	214.49	4,289,700
2021-01-15	Kulkarni Samarth (Chief Executive Officer)	Option Ex	20,000	1.81	36,200
2020-12-29	Kulkarni Samarth (Chief Executive Officer)	Option Ex	13,800	1.81	24,978
2020-12-21	Ho Tony W (Executive VP, Head of R&D)	Sale	23,551	149.69	3,525,349
2020-12-21	Ho Tony W (Executive VP, Head of R&D)	Option Ex	23,551	16.90	398,011
2020-12-16	Bolzon Bradley J Phd (Director)	Sale	15,000	149.12	2,236,785
2020-12-10	Kulkarni Samarth (Chief Executive Officer)	Sale	20,000	142.92	2,858,320
2020-12-10	Kulkarni Samarth (Chief Executive Officer)	Option Ex	20,000	1.81	36,200
2020-12-10	Bolzon Bradley J Phd (Director)	Sale	33,000	142.54	4,703,754

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Insider trading activities including stock purchases, stock sales, and option exercises of CRSP listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Crispr Therapeutics Ag (symbol CRSP, CIK number 1674416) see the Securities and Exchange Commission (SEC) website.

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