Insider Trading History of Gsk Plc

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Gsk Plc since 2015. This trader's CIK number is 1131399. At the time of last reporting, Gsk Plc was the Officer of Wave Life Sciences Ltd.. (stock ticker symbol WVE). Also see all insider trading activities at Wave Life Sciences Ltd..

Note that in the past GSK plc also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Genocea Biosciences, Inc. (GNCA) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	GNCA	1,260,504	$2,836,134	0	$0	0	$0
2019	GNCA	1,857,142	$6,499,997	0	$0	0	$0

Yearly summary of insider trading at Theravance Biopharma, Inc. (TBPH) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	TBPH	1,301,015	$29,959,728,534,982	0	$0	0	$0
2015	TBPH	44,574	$27,080,649,317	0	$0	0	$0

Yearly summary of insider trading at Bicycle Therapeutics Plc (BCYC) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	BCYC	0	$0	4,744	$91,598	0	$0
2019	BCYC	385,714	$5,399,996	0	$0	0	$0

Yearly summary of insider trading at Translate Bio, Inc. (TBIO) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	TBIO	269,230	$3,499,990	0	$0	0	$0

Yearly summary of insider trading at Pandion Therapeutics, Inc. (PAND) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	PAND	361,111	$6,499,998	0	$0	0	$0

Yearly summary of insider trading at Crispr Therapeutics Ag (CRSP) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	CRSP	66,500	$931,000	0	$0	0	$0

Yearly summary of insider trading at Decibel Therapeutics, Inc. (DBTX) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	DBTX	150,000	$2,700,000	0	$0	0	$0

Yearly summary of insider trading at Wave Life Sciences Ltd. (WVE) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2025	WVE	1,470,000	$27,930,000	0	$0	0	$0
2024	WVE	6,091,930	$38,835,440	0	$0	0	$0

Yearly summary of insider trading at Htg Molecular Diagnostics, Inc (HTGM) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2017	HTGM	0	$0	300,000	$3,045,300	0	$0
2015	HTGM	365,106	$5,111,484	0	$0	0	$0

Yearly summary of insider trading at Morphic Holding, Inc. (MORF) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	MORF	333,333	$4,999,995	0	$0	0	$0

Yearly summary of insider trading at Turning Point Therapeutics, Inc. (TPTX) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	TPTX	83,333	$4,999,980	0	$0	0	$0
2019	TPTX	502,777	$13,849,965	0	$0	0	$0

Yearly summary of insider trading at Nkarta, Inc. (NKTX) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	NKTX	833,333	$14,999,994	0	$0	0	$0

Yearly summary of insider trading at Innoviva, Inc. (INVA) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	INVA	0	$0	32,005,260	$392,064,435	0	$0
2015	INVA	424,081	$1,129,205,348,221	0	$0	0	$0

Yearly summary of insider trading at Liquidia Technologies Inc (LQDA) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	LQDA	148,818	$1,636,998	0	$0	0	$0

Yearly summary of insider trading at Applied Genetic Technologies Corp (AGTC) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	AGTC	0	$0	553,150	$12,127,023	0	$0

Yearly summary of insider trading at Cvrx, Inc. (CVRX) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	CVRX	275,000	$4,950,000	0	$0	0	$0

Yearly summary of insider trading at Spero Therapeutics, Inc. (SPRO) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	SPRO	80,000	$1,000,000	0	$0	0	$0
2017	SPRO	428,571	$5,999,994	0	$0	0	$0

Yearly summary of insider trading at Chemocentryx, Inc. (CCXI) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	CCXI	0	$0	7,343,492	$85,845,421	0	$0

Yearly summary of insider trading at Principia Biopharma Inc. (PRNB) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	PRNB	357,142	$9,999,976	0	$0	0	$0
2018	PRNB	270,000	$4,590,000	0	$0	0	$0

Yearly summary of insider trading at Progyny, Inc. (PGNY) by Gsk Plc

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	PGNY	0	$0	4,000,000	$103,000,000	0	$0

Insider trading activities at 20 companies by Gsk Plc:

1. Genocea Biosciences, Inc. (GNCA)

2. Theravance Biopharma, Inc. (TBPH)

3. Bicycle Therapeutics Plc (BCYC)

4. Translate Bio, Inc. (TBIO)

5. Pandion Therapeutics, Inc. (PAND)

6. Crispr Therapeutics Ag (CRSP)

7. Decibel Therapeutics, Inc. (DBTX)

8. Wave Life Sciences Ltd. (WVE)

9. Htg Molecular Diagnostics, Inc (HTGM)

10. Morphic Holding, Inc. (MORF)

11. Turning Point Therapeutics, Inc. (TPTX)

12. Nkarta, Inc. (NKTX)

13. Innoviva, Inc. (INVA)

14. Liquidia Technologies Inc (LQDA)

15. Applied Genetic Technologies Corp (AGTC)

16. Cvrx, Inc. (CVRX)

17. Spero Therapeutics, Inc. (SPRO)

18. Chemocentryx, Inc. (CCXI)

19. Principia Biopharma Inc. (PRNB)

20. Progyny, Inc. (PGNY)

Table 1. Insider trading of Genocea Biosciences, Inc. (GNCA) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-24	GNCA	Buy	1,260,504	2.25	2,836,134
2019-06-24	GNCA	Buy	1,857,142	3.50	6,499,997

Table 2. Insider trading of Theravance Biopharma, Inc. (TBPH) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-03-14	TBPH	Buy	1,301,015	23,027,965.50	29,959,728,534,982
2015-10-07	TBPH	Buy	44,574	607,543.62	27,080,649,317

Table 3. Insider trading of Bicycle Therapeutics Plc (BCYC) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-14	BCYC	Sale	1,597	19.27	30,780
2020-07-15	BCYC	Sale	3,147	19.33	60,818
2019-05-28	BCYC	Buy	385,714	14.00	5,399,996

Table 4. Insider trading of Translate Bio, Inc. (TBIO) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-07-02	TBIO	Buy	269,230	13.00	3,499,990

Table 5. Insider trading of Pandion Therapeutics, Inc. (PAND) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-21	PAND	Buy	361,111	18.00	6,499,998

Table 6. Insider trading of Crispr Therapeutics Ag (CRSP) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-10-24	CRSP	Buy	66,500	14.00	931,000

Table 7. Insider trading of Decibel Therapeutics, Inc. (DBTX) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-02-17	DBTX	Buy	150,000	18.00	2,700,000

Table 8. Insider trading of Wave Life Sciences Ltd. (WVE) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2025-12-11	WVE	Buy	1,470,000	19.00	27,930,000
2024-09-27	WVE	Buy	2,791,930	8.00	22,335,440
2023-12-07	WVE	Buy	3,300,000	5.00	16,500,000

Table 9. Insider trading of Htg Molecular Diagnostics, Inc (HTGM) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2017-03-27	HTGM	Sale	300,000	10.15	3,045,300
2015-05-11	HTGM	Buy	365,106	14.00	5,111,484

Table 10. Insider trading of Morphic Holding, Inc. (MORF) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-07-01	MORF	Buy	333,333	15.00	4,999,995

Table 11. Insider trading of Turning Point Therapeutics, Inc. (TPTX) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-05-21	TPTX	Buy	83,333	60.00	4,999,980
2019-09-10	TPTX	Buy	177,777	45.00	7,999,965
2019-04-22	TPTX	Buy	325,000	18.00	5,850,000

Table 12. Insider trading of Nkarta, Inc. (NKTX) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-14	NKTX	Buy	833,333	18.00	14,999,994

Table 13. Insider trading of Innoviva, Inc. (INVA) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-05-20	INVA	Sale	32,005,260	12.25	392,064,435
2015-08-07	THRX	Buy	245,828	3,485,841.04	856,917,331,181
2015-05-11	THRX	Buy	85,579	1,369,264.00	117,180,243,856
2015-03-02	THRX	Buy	92,674	1,673,692.44	155,107,773,184

Table 14. Insider trading of Liquidia Technologies Inc (LQDA) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-07-30	LQDA	Buy	148,818	11.00	1,636,998

Table 15. Insider trading of Applied Genetic Technologies Corp (AGTC) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-02-23	AGTC	Sale	503,150	22.00	11,069,803
2014-12-18	AGTC	Sale	12,000	21.01	252,132
2014-12-10	AGTC	Sale	10,000	21.18	211,759
2014-12-11	AGTC	Sale	12,500	21.28	266,037
2014-12-12	AGTC	Sale	7,500	21.24	159,292
2014-12-17	AGTC	Sale	8,000	21.00	168,000

Table 16. Insider trading of Cvrx, Inc. (CVRX) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-07-02	CVRX	Buy	275,000	18.00	4,950,000

Table 17. Insider trading of Spero Therapeutics, Inc. (SPRO) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-07-17	SPRO	Buy	80,000	12.50	1,000,000
2017-11-06	SPRO	Buy	428,571	14.00	5,999,994

Table 18. Insider trading of Chemocentryx, Inc. (CCXI) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-10-16	CCXI	Sale	7,343,492	11.69	85,845,421

Table 19. Insider trading of Principia Biopharma Inc. (PRNB) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-10-18	PRNB	Buy	357,142	28.00	9,999,976
2018-09-18	PRNB	Buy	270,000	17.00	4,590,000

Table 20. Insider trading of Progyny, Inc. (PGNY) by Gsk Plc

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-05-20	PGNY	Sale	4,000,000	25.75	103,000,000

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Gsk Plc (Officer of Wave Life Sciences Ltd. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

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