Insider Trading activities at Iteos Therapeutics, Inc. (ITOS)

Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Iteos Therapeutics, Inc. (ITOS) since 2020 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Iteos Therapeutics, Inc.. Table 2 shows the detailed insider transactions. This company's CIK number is 1808865.

Total stock buying since 2020: $133,923,239.
Total stock sales since 2020: $226,100,036.
Total stock option exercises since 2020: $3,652,137.

Table 1. Yearly summary of insider stock purchases, sales, and option exercises at *Iteos Therapeutics, Inc.* (*ITOS*).
	Insider Buying		Insider Sales		Option Exercises
Year	Shares	Value	Shares	Value	Shares	Value
2025	4,958,978	$38,686,391	2,668,407	$22,281,226	510,467	$2,195,004
2024	5,000	$38,635	0	$0	0	$0
2023	5,000	$41,849	350,000	$5,447,050	40,226	$118,666
2022	50,000	$1,640,919	2,971,592	$105,405,453	72,115	$345,920
2021	5,000	$130,445	3,027,020	$92,966,307	218,718	$992,547
2020	4,915,000	$93,385,000	0	$0	0	$0

Table 2. Monthly summary of insider trading at *Iteos Therapeutics, Inc.* (*ITOS*).
Trading Period	Insider Buying		Insider Sales		Option Exercises
year-month	Shares	Value	Shares	Value	Shares	Value
2025-06	0	$0	376,094	$3,805,185	488,121	$2,098,917
2025-05	4,958,978	$38,686,391	2,292,313	$18,476,041	22,346	$96,087
2024-11	5,000	$38,635	0	$0	0	$0
2023-10	5,000	$41,849	0	$0	0	$0
2023-08	0	$0	350,000	$5,447,050	0	$0
2023-03	0	$0	0	$0	40,226	$118,666
2022-06	0	$0	29,615	$597,784	29,615	$113,125
2022-05	0	$0	763,000	$16,483,095	0	$0
2022-04	0	$0	286,500	$7,933,107	11,500	$48,645
2022-03	50,000	$1,640,919	607,138	$21,411,416	13,500	$57,450
2022-02	0	$0	18,000	$630,377	3,500	$15,050
2022-01	0	$0	1,267,339	$58,349,674	14,000	$111,650
2021-12	0	$0	475,188	$17,355,495	90,500	$355,398
2021-11	0	$0	556,915	$19,819,252	44,263	$322,874
2021-10	0	$0	565,641	$15,399,029	14,429	$88,882
2021-09	0	$0	1,297,780	$36,533,046	0	$0
2021-08	0	$0	23,248	$653,367	0	$0
2021-07	0	$0	0	$0	53,672	$158,332
2021-06	5,000	$130,445	15,854	$318,441	15,854	$67,061
2021-04	0	$0	92,394	$2,887,677	0	$0
2020-07	4,915,000	$93,385,000	0	$0	0	$0

Table 3. Detailed insider trading at *Iteos Therapeutics, Inc.* (*ITOS*)
Trade Date	Insider Name	Trade Type	Shares	Price ($)	Value ($)
2025-06-10	Detheux Michel (Chief Executive Officer)	Sale	52,283	10.02	523,875
2025-06-10	Detheux Michel (Chief Executive Officer)	Option Ex	164,310	4.30	706,533
2025-06-09	Detheux Michel (Chief Executive Officer)	Sale	52,282	10.03	524,388
2025-06-09	Detheux Michel (Chief Executive Officer)	Option Ex	52,282	4.30	224,812
2025-06-06	Detheux Michel (Chief Executive Officer)	Sale	52,282	10.21	533,799
2025-06-06	Detheux Michel (Chief Executive Officer)	Option Ex	52,282	4.30	224,812
2025-06-06	Hallal David	Sale	38,228	10.24	391,454
2025-06-06	Hallal David	Option Ex	38,228	4.30	164,380
2025-06-05	Detheux Michel (Chief Executive Officer)	Sale	52,282	10.15	530,662
2025-06-05	Detheux Michel (Chief Executive Officer)	Option Ex	52,282	4.30	224,812
2025-06-05	Hallal David	Sale	38,227	10.15	388,004
2025-06-05	Hallal David	Option Ex	38,227	4.30	164,376
2025-06-04	Detheux Michel (Chief Executive Officer)	Sale	52,283	10.10	528,058
2025-06-04	Detheux Michel (Chief Executive Officer)	Option Ex	52,283	4.30	224,816
2025-06-04	Hallal David	Sale	38,227	10.07	384,945
2025-06-04	Hallal David	Option Ex	38,227	4.30	164,376
2025-05-15	Ecor1 Capital, Llc	Buy	3,300,000	8.00	26,400,000
2025-05-14	Ecor1 Capital, Llc	Buy	1,658,978	7.41	12,286,391
2025-05-13	Mpm Bioventures 2018 Gp Llc	Sale	630,191	8.06	5,079,339
2025-05-13	Van Hauwermeiren Timothy	Option Ex	22,346	4.30	96,087
2025-05-13	Ubs Oncology Impact Fund L.p.	Sale	1,031,931	8.06	8,317,363
2025-05-13	Foley Todd	Sale	630,191	8.06	5,079,339
2024-11-19	Gall Matthew (Chief Financial Officer)	Buy	5,000	7.73	38,635
2023-10-12	Gall Matthew (Chief Financial Officer)	Buy	5,000	8.37	41,849
2023-08-23	Davis Aaron I.	Sale	350,000	15.56	5,447,050
2023-03-28	Call Matthew (Chief Operating Officer)	Option Ex	40,226	2.95	118,666
2022-06-09	Hallal David (Director)	Sale	1,171	19.51	22,846
2022-06-09	Hallal David (Director)	Option Ex	1,171	4.23	4,953
2022-06-08	Hallal David (Director)	Sale	28,444	20.21	574,938
2022-06-08	Hallal David (Director)	Option Ex	28,444	3.80	108,172
2022-05-11	Davis Aaron I. (Director)	Sale	338,000	17.89	6,046,820
2022-05-10	Davis Aaron I. (Director)	Sale	100,000	24.97	2,497,300
2022-05-09	Davis Aaron I. (Director)	Sale	225,000	23.19	5,217,075
2022-05-02	Davis Aaron I. (Director)	Sale	100,000	27.22	2,721,900
2022-04-29	Davis Aaron I. (Director)	Sale	125,000	27.61	3,451,875
2022-04-28	Davis Aaron I. (Director)	Sale	150,000	27.40	4,110,300
2022-04-18	Detheux Michel (Chief Executive Officer)	Sale	11,500	32.26	370,932
2022-04-18	Detheux Michel (Chief Executive Officer)	Option Ex	11,500	4.23	48,645
2022-03-23	Davis Aaron I. (Director)	Buy	20,000	32.85	656,979
2022-03-22	Detheux Michel (Chief Executive Officer)	Sale	18,437	34.82	641,976
2022-03-22	Davis Aaron I. (Director)	Buy	30,000	32.80	983,940
2022-03-17	Lewis Joseph (10% Owner)	Sale	575,201	35.25	20,275,835
2022-03-11	Lager Joanne Jenkins (Chief Medical Officer)	Sale	3,500	36.01	126,035
2022-03-11	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	3,500	4.30	15,050
2022-03-01	Mcgrath Yvonne (Chief Scientific Officer)	Sale	10,000	36.76	367,570
2022-03-01	Mcgrath Yvonne (Chief Scientific Officer)	Option Ex	10,000	4.24	42,400
2022-02-23	Detheux Michel (Chief Executive Officer)	Sale	14,500	34.81	504,745
2022-02-11	Lager Joanne Jenkins (Chief Medical Officer)	Sale	3,500	35.90	125,632
2022-02-11	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	3,500	4.30	15,050
2022-01-25	Detheux Michel (Chief Executive Officer)	Sale	14,500	35.83	519,535
2022-01-14	Lager Joanne Jenkins (Chief Medical Officer)	Sale	3,500	39.41	137,952
2022-01-14	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	3,500	4.30	15,050
2022-01-05	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	18,135	42.03	762,214
2022-01-05	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	18,135	42.03	762,214
2022-01-05	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	30,347	42.03	1,275,484
2022-01-04	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	128,550	44.26	5,689,623
2022-01-04	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	128,550	44.26	5,689,623
2022-01-04	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	215,122	44.26	9,521,299
2022-01-04	Davis Aaron I. (Director)	Sale	184,677	43.78	8,085,159
2022-01-03	Biniszkiewicz Detlev (Director)	Sale	3,500	51.90	181,650
2022-01-03	Biniszkiewicz Detlev (Director)	Option Ex	3,500	19.00	66,500
2022-01-03	Lager Joanne Jenkins (Chief Medical Officer)	Sale	7,000	51.90	363,300
2022-01-03	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	7,000	4.30	30,100
2022-01-03	Davis Aaron I. (Director)	Sale	515,323	49.22	25,361,621
2021-12-27	Gall Matthew (Chief Financial Officer)	Sale	5,000	46.45	232,250
2021-12-22	Detheux Michel (Chief Executive Officer)	Sale	16,163	44.80	724,183
2021-12-22	Detheux Michel (Chief Executive Officer)	Option Ex	1,663	4.30	7,150
2021-12-21	Detheux Michel (Chief Executive Officer)	Sale	19,226	44.60	857,575
2021-12-21	Detheux Michel (Chief Executive Officer)	Option Ex	19,226	4.30	82,671
2021-12-20	Detheux Michel (Chief Executive Officer)	Sale	9,111	43.94	400,337
2021-12-20	Detheux Michel (Chief Executive Officer)	Option Ex	9,111	4.30	39,177
2021-12-20	Hallal David (Director)	Sale	50,000	43.57	2,178,500
2021-12-20	Hallal David (Director)	Option Ex	50,000	3.62	181,250
2021-12-17	Lager Joanne Jenkins (Chief Medical Officer)	Sale	7,000	41.00	287,000
2021-12-17	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	7,000	4.30	30,100
2021-12-10	Lager Joanne Jenkins (Chief Medical Officer)	Sale	3,500	34.50	120,750
2021-12-10	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	3,500	4.30	15,050
2021-12-07	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	19,456	33.63	654,305
2021-12-07	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	19,456	33.63	654,305
2021-12-07	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	32,558	33.63	1,094,925
2021-12-06	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	10,208	33.76	344,622
2021-12-06	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	10,208	33.76	344,622
2021-12-06	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	17,083	33.76	576,722
2021-12-03	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	20,167	35.46	715,121
2021-12-03	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	20,167	35.46	715,121
2021-12-03	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	33,749	35.46	1,196,739
2021-12-02	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	37,187	34.28	1,274,956
2021-12-02	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	37,187	34.28	1,274,956
2021-12-02	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	62,230	34.28	2,133,555
2021-12-01	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	12,395	34.59	428,743
2021-12-01	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	12,395	34.59	428,743
2021-12-01	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	20,742	34.59	717,465
2021-11-30	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	33,937	34.91	1,184,570
2021-11-30	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	33,937	34.91	1,184,570
2021-11-30	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	56,801	34.91	1,982,638
2021-11-29	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	10,371	34.91	362,103
2021-11-29	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	10,371	34.91	362,103
2021-11-29	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	17,356	34.91	605,984
2021-11-26	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	12,674	35.76	453,222
2021-11-26	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	12,674	35.76	453,222
2021-11-26	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	21,210	35.76	758,469
2021-11-24	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	36,337	36.09	1,311,402
2021-11-24	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	36,337	36.09	1,311,402
2021-11-24	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	60,808	36.09	2,194,560
2021-11-23	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	20,004	36.35	727,245
2021-11-23	Detheux Michel (Chief Executive Officer)	Sale	14,500	36.08	523,160
2021-11-23	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	20,004	36.35	727,245
2021-11-23	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	33,476	36.35	1,217,019
2021-11-22	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	21,114	37.48	791,458
2021-11-22	Detheux Michel (Chief Executive Officer)	Option Ex	16,263	12.45	202,474
2021-11-22	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	21,114	37.48	791,458
2021-11-22	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	35,333	37.48	1,324,457
2021-11-18	Lager Joanne Jenkins (Chief Medical Officer)	Sale	28,000	34.50	966,000
2021-11-18	Lager Joanne Jenkins (Chief Medical Officer)	Option Ex	28,000	4.30	120,400
2021-11-03	Detheux Michel (Chief Executive Officer)	Sale	6,085	28.89	175,777
2021-11-02	Detheux Michel (Chief Executive Officer)	Sale	14,391	28.41	408,920
2021-11-01	Detheux Michel (Chief Executive Officer)	Sale	81	28.00	2,268
2021-10-21	Detheux Michel (Chief Executive Officer)	Sale	196	28.00	5,488
2021-10-19	Detheux Michel (Chief Executive Officer)	Sale	201	28.00	5,628
2021-10-18	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	6,167	27.14	167,372
2021-10-18	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	6,167	27.14	167,372
2021-10-18	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	10,320	27.14	280,084
2021-10-15	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	10,932	27.77	303,581
2021-10-15	Detheux Michel (Chief Executive Officer)	Sale	1,635	28.01	45,796
2021-10-15	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	10,932	27.77	303,581
2021-10-15	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	18,295	27.77	508,052
2021-10-14	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	27,320	27.30	745,836
2021-10-14	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	27,320	27.30	745,836
2021-10-14	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	45,719	27.30	1,248,128
2021-10-13	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	20,929	27.13	567,803
2021-10-13	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	20,929	27.13	567,803
2021-10-13	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	35,023	27.13	950,173
2021-10-12	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	8,521	27.09	230,833
2021-10-12	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	8,521	27.09	230,833
2021-10-12	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	14,260	27.09	386,303
2021-10-11	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	48,812	27.24	1,329,638
2021-10-11	Gall Matthew (Chief Financial Officer)	Option Ex	14,429	6.16	88,882
2021-10-11	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	48,812	27.24	1,329,638
2021-10-11	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	81,684	27.24	2,225,072
2021-10-08	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	2,032	27.01	54,884
2021-10-08	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	2,032	27.01	54,884
2021-10-08	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	3,400	27.01	91,834
2021-10-07	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	1,149	27.00	31,023
2021-10-07	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	1,149	27.00	31,023
2021-10-07	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	1,922	27.00	51,894
2021-10-04	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	20,711	27.06	560,439
2021-10-04	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	20,711	27.06	560,439
2021-10-04	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	34,659	27.06	937,872
2021-10-01	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	6,855	27.00	185,085
2021-10-01	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	6,855	27.00	185,085
2021-10-01	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	11,471	27.00	309,717
2021-09-30	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	2,292	27.00	61,884
2021-09-30	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	2,292	27.00	61,884
2021-09-30	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	3,836	27.00	103,572
2021-09-28	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	19,214	27.00	518,778
2021-09-28	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	19,214	27.00	518,778
2021-09-28	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	32,154	27.00	868,158
2021-09-27	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	11,625	27.09	314,921
2021-09-27	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	11,625	27.09	314,921
2021-09-27	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	19,455	27.09	527,035
2021-09-24	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	4,913	27.81	136,630
2021-09-24	Detheux Michel (Chief Executive Officer)	Sale	1,089	28.02	30,511
2021-09-24	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	4,913	27.81	136,630
2021-09-24	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	8,221	27.81	228,626
2021-09-23	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	36,930	28.17	1,040,318
2021-09-23	Detheux Michel (Chief Executive Officer)	Sale	5,322	28.16	149,862
2021-09-23	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	36,930	28.17	1,040,318
2021-09-23	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	61,800	28.17	1,740,906
2021-09-22	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	14,294	27.54	393,656
2021-09-22	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	14,294	27.54	393,656
2021-09-22	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	23,921	27.54	658,784
2021-09-21	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	19,635	27.47	539,373
2021-09-21	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	19,635	27.47	539,373
2021-09-21	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	32,858	27.47	902,609
2021-09-20	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	24,303	27.43	666,752
2021-09-20	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	24,303	27.43	666,752
2021-09-20	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	40,673	27.43	1,115,863
2021-09-17	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	45,698	28.82	1,317,016
2021-09-17	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	45,698	28.82	1,317,016
2021-09-17	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	76,473	28.82	2,203,951
2021-09-16	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	21,253	28.47	605,072
2021-09-16	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	21,253	28.47	605,072
2021-09-16	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	35,565	28.47	1,012,535
2021-09-15	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	24,104	27.97	674,188
2021-09-15	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	24,104	27.97	674,188
2021-09-15	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	40,336	27.97	1,128,197
2021-09-14	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	21,561	27.75	598,209
2021-09-14	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	21,561	27.75	598,209
2021-09-14	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	36,081	27.75	1,001,067
2021-09-13	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	21,384	27.64	591,053
2021-09-13	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	21,384	27.64	591,053
2021-09-13	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	35,785	27.64	989,097
2021-09-10	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	13,531	28.30	382,859
2021-09-10	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	13,531	28.30	382,859
2021-09-10	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	22,643	28.30	640,683
2021-09-09	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	22,725	28.97	658,343
2021-09-09	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	22,725	28.97	658,343
2021-09-09	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	38,028	28.97	1,101,671
2021-09-08	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	12,092	28.86	348,914
2021-09-08	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	12,092	28.86	348,914
2021-09-08	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	20,236	28.86	583,909
2021-09-07	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	30,474	29.18	889,231
2021-09-07	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	30,474	29.18	889,231
2021-09-07	Oncology Impact Fund (cayman) Management L.p. (10% Owner)	Sale	50,996	29.18	1,488,063
2021-09-02	Detheux Michel (Chief Executive Officer)	Sale	11,568	29.20	337,831
2021-09-01	Detheux Michel (Chief Executive Officer)	Sale	8,684	28.30	245,722
2021-08-31	Detheux Michel (Chief Executive Officer)	Sale	4,093	28.12	115,095
2021-08-30	Detheux Michel (Chief Executive Officer)	Sale	2,322	28.01	65,039
2021-08-27	Detheux Michel (Chief Executive Officer)	Sale	8,248	28.17	232,346
2021-08-25	Detheux Michel (Chief Executive Officer)	Sale	861	28.00	24,108
2021-08-24	Detheux Michel (Chief Executive Officer)	Sale	225	28.26	6,358
2021-08-23	Detheux Michel (Chief Executive Officer)	Sale	7,499	28.06	210,421
2021-07-30	Call Matthew (Chief Operating Officer)	Option Ex	53,672	2.95	158,332
2021-06-16	Gall Matthew (Chief Financial Officer)	Buy	5,000	26.09	130,445
2021-06-08	Mcgrath Yvonne (VP, Research and Development)	Sale	7,927	20.00	158,540
2021-06-08	Mcgrath Yvonne (VP, Research and Development)	Option Ex	7,927	4.23	33,531
2021-06-02	Mcgrath Yvonne (VP, Research and Development)	Sale	323	20.00	6,460
2021-06-02	Mcgrath Yvonne (VP, Research and Development)	Option Ex	323	4.23	1,366
2021-06-01	Mcgrath Yvonne (VP, Research and Development)	Sale	7,604	20.18	153,441
2021-06-01	Mcgrath Yvonne (VP, Research and Development)	Option Ex	7,604	4.23	32,164
2021-04-09	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	119	29.99	3,568
2021-04-09	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	119	29.99	3,568
2021-04-08	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	19,304	30.76	593,791
2021-04-08	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	19,304	30.76	593,791
2021-04-08	Mpm Oncology Impact Management Gp Llc (10% Owner)	Sale	32,304	30.76	993,671
2021-04-07	Mpm Bioventures 2018 Gp Llc (10% Owner)	Sale	5,783	32.92	190,359
2021-04-07	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Sale	5,783	32.92	190,359
2021-04-07	Mpm Oncology Impact Management Gp Llc (10% Owner)	Sale	9,678	32.92	318,570
2020-07-28	Mpm Bioventures 2018 Gp Llc (10% Owner)	Buy	160,000	19.00	3,040,000
2020-07-28	Mpm Asset Management Investors Bv2018 Llc (10% Owner)	Buy	160,000	19.00	3,040,000
2020-07-28	Oncology Impact Fund (cayman) Management L.p. (Other)	Buy	320,000	19.00	6,080,000
2020-07-28	Shah Rajeev M.	Buy	1,425,000	19.00	27,075,000
2020-07-28	Mva Investors, Llc (10% Owner)	Buy	1,425,000	19.00	27,075,000
2020-07-28	Davis Aaron I. (Director)	Buy	1,425,000	19.00	27,075,000

Insider trading activities including stock purchases, stock sales, and option exercises of ITOS listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Iteos Therapeutics, Inc. (symbol ITOS, CIK number 1808865) see the Securities and Exchange Commission (SEC) website.

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