Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Denali Therapeutics Inc. (DNLI) since 2017 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Denali Therapeutics Inc.. Table 2 shows the detailed insider transactions. This company's CIK number is 1714899.
Total stock buying since 2017: $4,950,000.
Total stock sales since 2017: $369,839,556.
Total stock option exercises since 2017: $3,381,374.
| Insider Buying | Insider Sales | Option Exercises | ||||
|---|---|---|---|---|---|---|
| Year | Shares | Value | Shares | Value | Shares | Value |
| 2025 | 0 | $0 | 572,541 | $8,957,815 | 539,937 | $1,506,305 |
| 2024 | 0 | $0 | 269,222 | $6,300,138 | 150,627 | $204,848 |
| 2023 | 0 | $0 | 206,340 | $5,709,552 | 132,526 | $228,116 |
| 2022 | 0 | $0 | 137,261 | $4,688,932 | 153,249 | $582,472 |
| 2021 | 0 | $0 | 3,098,751 | $199,729,082 | 52,376 | $6,150 |
| 2020 | 0 | $0 | 4,481,411 | $131,544,541 | 69,835 | $279,343 |
| 2019 | 0 | $0 | 447,952 | $9,327,563 | 109,827 | $490,494 |
| 2018 | 0 | $0 | 186,667 | $3,581,933 | 12,961 | $83,646 |
| 2017 | 275,000 | $4,950,000 | 0 | $0 | 0 | $0 |
| Trading Period | Insider Buying | Insider Sales | Option Exercises | |||
|---|---|---|---|---|---|---|
| year-month | Shares | Value | Shares | Value | Shares | Value |
| 2025-08 | 0 | $0 | 6,680 | $91,567 | 44,655 | $30,365 |
| 2025-07 | 0 | $0 | 495,282 | $7,429,230 | 495,282 | $1,475,940 |
| 2025-01 | 0 | $0 | 70,579 | $1,437,018 | 0 | $0 |
| 2024-12 | 0 | $0 | 0 | $0 | 6,708 | $35,418 |
| 2024-11 | 0 | $0 | 19,658 | $589,474 | 53,919 | $108,230 |
| 2024-10 | 0 | $0 | 40,000 | $1,107,600 | 40,000 | $27,200 |
| 2024-09 | 0 | $0 | 34,100 | $979,054 | 0 | $0 |
| 2024-08 | 0 | $0 | 39,407 | $953,040 | 0 | $0 |
| 2024-07 | 0 | $0 | 33,080 | $743,069 | 0 | $0 |
| 2024-06 | 0 | $0 | 2,146 | $46,673 | 0 | $0 |
| 2024-05 | 0 | $0 | 1,674 | $34,132 | 0 | $0 |
| 2024-04 | 0 | $0 | 1,666 | $30,471 | 0 | $0 |
| 2024-03 | 0 | $0 | 1,666 | $33,486 | 0 | $0 |
| 2024-02 | 0 | $0 | 41,038 | $719,492 | 50,000 | $34,000 |
| 2024-01 | 0 | $0 | 54,787 | $1,063,647 | 0 | $0 |
| 2023-12 | 0 | $0 | 1,666 | $38,967 | 0 | $0 |
| 2023-11 | 0 | $0 | 1,666 | $31,870 | 0 | $0 |
| 2023-10 | 0 | $0 | 1,666 | $34,419 | 0 | $0 |
| 2023-09 | 0 | $0 | 1,666 | $39,942 | 0 | $0 |
| 2023-08 | 0 | $0 | 29,170 | $686,355 | 2,526 | $1,717 |
| 2023-07 | 0 | $0 | 21,368 | $636,470 | 10,000 | $52,800 |
| 2023-06 | 0 | $0 | 1,666 | $49,588 | 0 | $0 |
| 2023-05 | 0 | $0 | 10,000 | $288,900 | 10,000 | $52,800 |
| 2023-04 | 0 | $0 | 35,000 | $879,119 | 35,000 | $69,799 |
| Trade Date | Insider Name | Trade Type | Shares | Price ($) | Value ($) |
|---|---|---|---|---|---|
| 2025-08-13 | Ho Carole (Chief Medical Officer) | Sale | 806 | 14.64 | 11,799 |
| 2025-08-12 | Ho Carole (Chief Medical Officer) | Sale | 2,937 | 13.58 | 39,884 |
| 2025-08-12 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,937 | 13.58 | 39,884 |
| 2025-08-05 | Ho Carole (Chief Medical Officer) | Option Ex | 44,655 | .68 | 30,365 |
| 2025-07-09 | Watts Ryan J. (President and CEO) | Sale | 495,282 | 15.00 | 7,429,230 |
| 2025-07-09 | Watts Ryan J. (President and CEO) | Option Ex | 495,282 | 2.98 | 1,475,940 |
| 2025-01-07 | Ho Carole (Chief Medical Officer) | Sale | 2,907 | 20.81 | 60,494 |
| 2025-01-07 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,907 | 20.81 | 60,494 |
| 2025-01-07 | Watts Ryan J. (President and CEO) | Sale | 7,650 | 20.81 | 159,196 |
| 2025-01-07 | Krognes Steve E. | Sale | 3,339 | 20.81 | 69,484 |
| 2025-01-06 | Ho Carole (Chief Medical Officer) | Sale | 12,255 | 20.22 | 247,796 |
| 2025-01-06 | Schuth Alexander O. (COFO and Secretary) | Sale | 12,255 | 20.22 | 247,796 |
| 2025-01-06 | Watts Ryan J. (President and CEO) | Sale | 29,266 | 20.22 | 591,758 |
| 2024-12-27 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 6,708 | 5.28 | 35,418 |
| 2024-11-25 | Ho Carole (Chief Medical Officer) | Option Ex | 17,845 | .68 | 12,134 |
| 2024-11-22 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 20,516 | .68 | 13,950 |
| 2024-11-07 | Schuth Alexander O. (COFO and Secretary) | Sale | 15,558 | 30.56 | 475,499 |
| 2024-11-07 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 15,558 | 5.28 | 82,146 |
| 2024-11-07 | Sato Vicki L (Director) | Sale | 1,020 | 30.00 | 30,600 |
| 2024-11-01 | Sato Vicki L (Director) | Sale | 3,080 | 27.07 | 83,375 |
| 2024-10-18 | Watts Ryan J. (President and CEO) | Sale | 40,000 | 27.69 | 1,107,600 |
| 2024-10-18 | Watts Ryan J. (President and CEO) | Option Ex | 40,000 | .68 | 27,200 |
| 2024-09-30 | Krognes Steve E. | Sale | 30,000 | 29.03 | 870,900 |
| 2024-09-13 | Sato Vicki L (Director) | Sale | 1,020 | 30.00 | 30,600 |
| 2024-09-03 | Sato Vicki L (Director) | Sale | 3,080 | 25.18 | 77,554 |
| 2024-08-21 | Ho Carole (Chief Medical Officer) | Sale | 20,005 | 24.68 | 493,823 |
| 2024-08-21 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,547 | 24.78 | 63,114 |
| 2024-08-20 | Ho Carole (Chief Medical Officer) | Sale | 2,453 | 23.79 | 58,356 |
| 2024-08-20 | Schuth Alexander O. (COFO and Secretary) | Sale | 5,806 | 23.66 | 137,398 |
| 2024-08-20 | Watts Ryan J. (President and CEO) | Sale | 2,260 | 23.79 | 53,765 |
| 2024-08-20 | Krognes Steve E. | Sale | 1,727 | 23.79 | 41,085 |
| 2024-08-13 | Ho Carole (Chief Medical Officer) | Sale | 2,337 | 22.89 | 53,493 |
| 2024-08-13 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,272 | 22.89 | 52,006 |
| 2024-07-01 | Krognes Steve E. | Sale | 30,000 | 22.46 | 673,800 |
| 2024-07-01 | Sato Vicki L (Director) | Sale | 3,080 | 22.49 | 69,269 |
| 2024-06-13 | Krognes Steve E. | Sale | 688 | 21.79 | 14,991 |
| 2024-06-06 | Cook Jennifer E. (Director) | Sale | 1,458 | 21.73 | 31,682 |
| 2024-05-15 | Sato Vicki L (Director) | Sale | 1,674 | 20.39 | 34,132 |
| 2024-04-15 | Sato Vicki L (Director) | Sale | 1,666 | 18.29 | 30,471 |
| 2024-03-15 | Sato Vicki L (Director) | Sale | 1,666 | 20.10 | 33,486 |
| 2024-02-15 | Sato Vicki L (Director) | Sale | 1,666 | 18.37 | 30,604 |
| 2024-02-14 | Ho Carole (Chief Medical Officer) | Sale | 1,405 | 17.79 | 24,994 |
| 2024-02-14 | Schuth Alexander O. (COFO and Secretary) | Sale | 20,128 | 17.66 | 355,460 |
| 2024-02-13 | Ho Carole (Chief Medical Officer) | Sale | 2,784 | 17.29 | 48,135 |
| 2024-02-13 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,716 | 17.29 | 46,959 |
| 2024-02-13 | Watts Ryan J. (President and CEO) | Sale | 9,589 | 17.29 | 165,793 |
| 2024-02-13 | Krognes Steve E. | Sale | 2,750 | 17.29 | 47,547 |
| 2024-02-08 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 50,000 | .68 | 34,000 |
| 2024-01-16 | Sato Vicki L (Director) | Sale | 1,666 | 18.42 | 30,687 |
| 2024-01-10 | Ho Carole (Chief Medical Officer) | Sale | 4,668 | 19.02 | 88,785 |
| 2024-01-09 | Watts Ryan J. (President and CEO) | Sale | 7,818 | 19.78 | 154,640 |
| 2024-01-05 | Ho Carole (Chief Medical Officer) | Sale | 9,972 | 19.43 | 193,755 |
| 2024-01-05 | Schuth Alexander O. (COFO and Secretary) | Sale | 9,972 | 19.43 | 193,755 |
| 2024-01-05 | Watts Ryan J. (President and CEO) | Sale | 17,483 | 19.43 | 339,694 |
| 2024-01-05 | Krognes Steve E. | Sale | 3,208 | 19.43 | 62,331 |
| 2023-12-15 | Sato Vicki L (Director) | Sale | 1,666 | 23.39 | 38,967 |
| 2023-11-15 | Sato Vicki L (Director) | Sale | 1,666 | 19.13 | 31,870 |
| 2023-10-16 | Sato Vicki L (Director) | Sale | 1,666 | 20.66 | 34,419 |
| 2023-09-15 | Sato Vicki L (Director) | Sale | 1,666 | 23.98 | 39,942 |
| 2023-08-23 | Ho Carole (Chief Medical Officer) | Sale | 2,522 | 23.22 | 58,560 |
| 2023-08-23 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,522 | 23.17 | 58,434 |
| 2023-08-21 | Ho Carole (Chief Medical Officer) | Sale | 2,478 | 22.60 | 56,002 |
| 2023-08-21 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,478 | 22.59 | 55,978 |
| 2023-08-21 | Watts Ryan J. (President and CEO) | Sale | 2,309 | 22.59 | 52,160 |
| 2023-08-21 | Krognes Steve E. | Sale | 1,419 | 22.60 | 32,069 |
| 2023-08-15 | Sato Vicki L (Director) | Sale | 1,666 | 24.30 | 40,483 |
| 2023-08-14 | Ho Carole (Chief Medical Officer) | Sale | 2,768 | 23.79 | 65,850 |
| 2023-08-14 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,772 | 23.67 | 65,613 |
| 2023-08-10 | Ho Carole (Chief Medical Officer) | Sale | 2,857 | 24.15 | 68,996 |
| 2023-08-10 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,853 | 24.18 | 68,985 |
| 2023-08-10 | Watts Ryan J. (President and CEO) | Sale | 2,526 | 25.03 | 63,225 |
| 2023-08-10 | Watts Ryan J. (President and CEO) | Option Ex | 2,526 | .68 | 1,717 |
| 2023-07-18 | Schuth Alexander O. (COFO and Secretary) | Sale | 9,702 | 30.01 | 291,157 |
| 2023-07-17 | Schuth Alexander O. (COFO and Secretary) | Sale | 10,000 | 29.60 | 296,000 |
| 2023-07-17 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 10,000 | 5.28 | 52,800 |
| 2023-07-17 | Sato Vicki L (Director) | Sale | 1,666 | 29.60 | 49,313 |
| 2023-06-28 | Sato Vicki L (Director) | Sale | 1,666 | 29.77 | 49,588 |
| 2023-05-15 | Schuth Alexander O. (COFO and Secretary) | Sale | 10,000 | 28.89 | 288,900 |
| 2023-05-15 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 10,000 | 5.28 | 52,800 |
| 2023-04-21 | Watts Ryan J. (President and CEO) | Sale | 24,800 | 25.15 | 623,720 |
| 2023-04-21 | Watts Ryan J. (President and CEO) | Option Ex | 24,800 | .68 | 16,864 |
| 2023-04-20 | Watts Ryan J. (President and CEO) | Sale | 200 | 25.00 | 5,000 |
| 2023-04-20 | Watts Ryan J. (President and CEO) | Option Ex | 200 | .68 | 136 |
| 2023-04-13 | Schuth Alexander O. (COFO and Secretary) | Sale | 4,898 | 25.04 | 122,645 |
| 2023-04-13 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 4,898 | 5.28 | 25,861 |
| 2023-04-12 | Schuth Alexander O. (COFO and Secretary) | Sale | 5,102 | 25.04 | 127,754 |
| 2023-04-12 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 5,102 | 5.28 | 26,938 |
| 2023-02-15 | Ho Carole (Chief Medical Officer) | Sale | 1,476 | 29.40 | 43,394 |
| 2023-02-13 | Ho Carole (Chief Medical Officer) | Sale | 2,548 | 30.10 | 76,694 |
| 2023-02-13 | Schuth Alexander O. (COFO and Secretary) | Sale | 3,497 | 30.09 | 105,224 |
| 2023-02-13 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 25,000 | .68 | 17,000 |
| 2023-02-13 | Watts Ryan J. (President and CEO) | Sale | 33,815 | 30.09 | 1,017,324 |
| 2023-02-13 | Watts Ryan J. (President and CEO) | Option Ex | 25,000 | .68 | 17,000 |
| 2023-02-13 | Krognes Steve E. | Sale | 2,119 | 30.10 | 63,781 |
| 2023-02-10 | Ho Carole (Chief Medical Officer) | Sale | 818 | 29.80 | 24,376 |
| 2023-02-10 | Watts Ryan J. (President and CEO) | Sale | 25,000 | 29.10 | 727,500 |
| 2023-02-10 | Watts Ryan J. (President and CEO) | Option Ex | 25,000 | .68 | 17,000 |
| 2023-02-09 | Watts Ryan J. (President and CEO) | Sale | 3,433 | 30.59 | 105,015 |
| 2023-02-08 | Ho Carole (Chief Medical Officer) | Sale | 1,521 | 30.88 | 46,968 |
| 2023-02-08 | Schuth Alexander O. (COFO and Secretary) | Sale | 1,521 | 30.89 | 46,983 |
| 2023-02-08 | Krognes Steve E. | Sale | 1,377 | 30.88 | 42,521 |
| 2023-01-06 | Ho Carole (Chief Medical Officer) | Sale | 1,451 | 28.67 | 41,600 |
| 2023-01-05 | Ho Carole (Chief Medical Officer) | Sale | 2,636 | 28.44 | 74,967 |
| 2023-01-05 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,636 | 28.44 | 74,967 |
| 2023-01-05 | Watts Ryan J. (President and CEO) | Sale | 4,800 | 28.44 | 136,512 |
| 2023-01-05 | Krognes Steve E. | Sale | 2,970 | 28.44 | 84,466 |
| 2023-01-04 | Ho Carole (Chief Medical Officer) | Sale | 2,913 | 28.69 | 83,573 |
| 2023-01-04 | Schuth Alexander O. (COFO and Secretary) | Sale | 2,912 | 28.70 | 83,574 |
| 2023-01-04 | Watts Ryan J. (President and CEO) | Sale | 5,029 | 28.73 | 144,483 |
| 2022-11-23 | Tessier-lavigne Marc | Sale | 20,000 | 30.48 | 609,600 |
| 2022-10-07 | Schuth Alexander O. (COFO and Secretary) | Option Ex | 20,000 | .68 | 13,600 |
| 2022-09-28 | Tessier-lavigne Marc | Sale | 20,000 | 30.91 | 618,200 |
| 2022-08-23 | Ho Carole (Chief Medical Officer) | Sale | 2,424 | 31.98 | 77,519 |
| 2022-08-23 | Tessier-lavigne Marc | Sale | 20,000 | 32.02 | 640,400 |
| 2022-07-25 | Tessier-lavigne Marc | Sale | 20,000 | 35.88 | 717,500 |
| 2022-07-19 | Krognes Steve E. | Option Ex | 62,500 | .68 | 42,500 |
| 2022-03-23 | Tessier-lavigne Marc | Sale | 20,000 | 33.77 | 675,400 |
| 2022-02-11 | Ho Carole (Chief Medical Officer) | Sale | 2,918 | 34.71 | 101,283 |
| 2022-02-11 | Schuth Alexander O. (COO and Secretary) | Sale | 2,803 | 34.68 | 97,208 |
| 2022-02-11 | Watts Ryan J. (President and CEO) | Sale | 9,491 | 34.72 | 329,527 |
| 2022-02-11 | Krognes Steve E. (CFO and Treasurer) | Sale | 2,560 | 34.69 | 88,806 |
| 2022-02-10 | Watts Ryan J. (President and CEO) | Option Ex | 70,749 | 7.44 | 526,372 |
| 2022-02-09 | Ho Carole (Chief Medical Officer) | Sale | 1,423 | 37.10 | 52,791 |
| 2022-02-09 | Watts Ryan J. (President and CEO) | Sale | 2,719 | 37.55 | 102,103 |
| 2022-01-05 | Ho Carole (Chief Medical Officer) | Sale | 2,845 | 44.78 | 127,399 |
| 2022-01-05 | Schuth Alexander O. (COO and Secretary) | Sale | 2,846 | 44.77 | 127,415 |
| 2022-01-05 | Watts Ryan J. (President and CEO) | Sale | 5,007 | 44.78 | 224,213 |
| 2022-01-05 | Krognes Steve E. (CFO and Treasurer) | Sale | 2,225 | 44.75 | 99,568 |
| 2021-12-30 | Tessier-lavigne Marc | Sale | 20,047 | 45.46 | 911,376 |
| 2021-12-29 | Tessier-lavigne Marc | Sale | 32,104 | 43.88 | 1,408,627 |
| 2021-12-28 | Tessier-lavigne Marc | Sale | 10,980 | 44.37 | 487,215 |
| 2021-12-06 | Ho Carole (Chief Medical Officer) | Sale | 1,476 | 42.52 | 62,759 |
| 2021-12-06 | Schuth Alexander O. (COO and Secretary) | Sale | 10,000 | 42.13 | 421,350 |
| 2021-12-01 | Watts Ryan J. (President and CEO) | Sale | 18,333 | 45.35 | 831,346 |
| 2021-11-04 | Schuth Alexander O. (COO and Secretary) | Sale | 10,000 | 52.94 | 529,400 |
| 2021-11-01 | Watts Ryan J. (President and CEO) | Sale | 18,333 | 49.24 | 902,716 |
| 2021-11-01 | Sato Vicki L | Sale | 1,666 | 50.05 | 83,383 |
| 2021-10-04 | Schuth Alexander O. (COO and Secretary) | Sale | 10,000 | 50.64 | 506,400 |
| 2021-10-01 | Watts Ryan J. (President and CEO) | Sale | 18,333 | 50.27 | 921,599 |
| 2021-09-20 | Schuth Alexander O. (COO and Secretary) | Option Ex | 9,045 | .68 | 6,150 |
| 2021-09-15 | Sato Vicki L | Sale | 1,666 | 53.50 | 89,127 |
| 2021-09-07 | Schuth Alexander O. (COO and Secretary) | Sale | 10,000 | 55.47 | 554,730 |
| 2021-09-01 | Watts Ryan J. (President and CEO) | Sale | 18,333 | 54.59 | 1,000,890 |
| 2021-08-23 | Ho Carole (Chief Medical Officer) | Sale | 6,143 | 48.91 | 300,454 |
| 2021-08-19 | Ho Carole (Chief Medical Officer) | Sale | 2,546 | 49.61 | 126,307 |
| 2021-08-19 | Schuth Alexander O. (COO and Secretary) | Sale | 2,544 | 49.83 | 126,767 |
| 2021-08-19 | Watts Ryan J. (President and CEO) | Sale | 2,376 | 49.67 | 118,027 |
| 2021-08-19 | Krognes Steve E. (CFO and Treasurer) | Sale | 2,285 | 49.80 | 113,781 |
| 2021-08-18 | Sato Vicki L | Sale | 1,666 | 51.69 | 86,115 |
| 2021-08-04 | Schuth Alexander O. (COO and Secretary) | Sale | 10,000 | 52.28 | 522,819 |
Insider trading activities including stock purchases, stock sales, and option exercises of DNLI listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Denali Therapeutics Inc. (symbol DNLI, CIK number 1714899) see the Securities and Exchange Commission (SEC) website.