Insider Trading activities at Amylyx Pharmaceuticals, Inc. (AMLX)

Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Amylyx Pharmaceuticals, Inc. (AMLX) since 2022 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Amylyx Pharmaceuticals, Inc.. Table 2 shows the detailed insider transactions. This company's CIK number is 1658551.

Total stock buying since 2022: $50,096,034.
Total stock sales since 2022: $82,884,015.
Total stock option exercises since 2022: $1,184,262.


17 insiders reported insider trading activities at Amylyx Pharmaceuticals, Inc. (AMLX):
Insider trading activities of Firestone Karen
Insider trading activities of Zeiher Bernhardt G
Insider trading activities of Mazzariello Gina
Insider trading activities of Shabet Rose Sharon
Insider trading activities of Morningside Venture Investments Ltd
Insider trading activities of Olinger Margaret
Insider trading activities of Quimi Daphne
Insider trading activities of Cohen Joshua B
Insider trading activities of Fonteyne Paul R.
Insider trading activities of Yeramian Patrick D
Insider trading activities of Dragsa 96 Llc
Insider trading activities of Als Invest 1 B.v.
Insider trading activities of Milne George M Jr
Insider trading activities of Bedrosian Camille L
Insider trading activities of Frates James M
Insider trading activities of Klee Justin B.
Insider trading activities of Cheng Isaac

Table 1. Yearly summary of insider stock purchases, sales, and option exercises at Amylyx Pharmaceuticals, Inc. (AMLX).
Insider Buying Insider Sales Option Exercises
Year Shares Value Shares Value Shares Value
2025 10,000 $37,010 158,194 $696,138 36,310 $57,006
2024 195,000 $437,194 104,855 $784,410 99,996 $156,992
2023 5,000 $91,870 1,162,962 $37,981,997 220,903 $688,320
2022 2,606,840 $49,529,960 1,460,609 $43,421,470 674,040 $281,944

Table 2. Monthly summary of insider trading at Amylyx Pharmaceuticals, Inc. (AMLX).
Trading Period Insider Buying Insider Sales Option Exercises
year-month Shares Value Shares Value Shares Value
2025-08 0 $0 30,000 $246,150 0 $0
2025-03 10,000 $37,010 81,699 $281,353 0 $0
2025-02 0 $0 31,553 $108,195 36,310 $57,006
2025-01 0 $0 14,942 $60,440 0 $0
2024-12 0 $0 5,421 $30,005 0 $0
2024-11 0 $0 0 $0 63,690 $99,993
2024-09 190,000 $427,759 57,329 $183,238 36,306 $56,999
2024-05 5,000 $9,435 10,455 $19,655 0 $0
2024-03 0 $0 11,602 $217,281 0 $0
2024-02 0 $0 2,838 $53,229 0 $0
2024-01 0 $0 17,210 $281,002 0 $0
2023-12 4,000 $59,880 0 $0 25,000 $9,250
2023-11 0 $0 0 $0 63,694 $99,999
2023-08 0 $0 0 $0 18,165 $124,975
2023-07 0 $0 0 $0 20,000 $7,400
2023-05 0 $0 44,465 $1,233,402 44,465 $266,973
2023-04 0 $0 49,579 $1,523,909 49,579 $179,723
2023-03 1,000 $31,990 846,301 $27,304,643 0 $0
2023-02 0 $0 203,586 $7,226,670 0 $0
2023-01 0 $0 19,031 $693,373 0 $0
2022-12 0 $0 0 $0 5,000 $34,400
2022-09 0 $0 1,400,000 $42,150,500 0 $0
2022-07 0 $0 60,609 $1,270,970 0 $0
2022-05 0 $0 0 $0 669,040 $247,544

Table 3. Detailed insider trading at Amylyx Pharmaceuticals, Inc. (AMLX)
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2025-08-13 Mazzariello Gina (Chief Legal Officer) Sale 15,000 8.34 125,040
2025-08-12 Mazzariello Gina (Chief Legal Officer) Sale 15,000 8.07 121,110
2025-03-31 Mazzariello Gina (Chief Legal Officer) Sale 9,192 3.48 31,951
2025-03-31 Cohen Joshua B (Co-Chief Executive Officer) Sale 21,490 3.47 74,484
2025-03-31 Klee Justin B. (Co-Chief Executive Officer) Sale 21,490 3.46 74,462
2025-03-31 Bedrosian Camille L (Chief Medical Officer) Sale 12,425 3.47 43,077
2025-03-31 Frates James M (Chief Financial Officer) Sale 10,896 3.47 37,809
2025-03-20 Zeiher Bernhardt G Buy 10,000 3.70 37,010
2025-03-03 Mazzariello Gina (Chief Legal Officer) Sale 1,611 3.12 5,023
2025-03-03 Cohen Joshua B (Co-Chief Executive Officer) Sale 4,595 3.17 14,547
2025-02-24 Mazzariello Gina (Chief Legal Officer) Sale 4,169 3.15 13,144
2025-02-05 Klee Justin B. (Co-Chief Executive Officer) Option Ex 36,310 1.57 57,006
2025-02-03 Mazzariello Gina (Chief Legal Officer) Sale 3,678 3.49 12,839
2025-02-03 Cohen Joshua B (Co-Chief Executive Officer) Sale 11,851 3.47 41,111
2025-02-03 Klee Justin B. (Co-Chief Executive Officer) Sale 11,855 3.47 41,101
2025-01-06 Cohen Joshua B (Co-Chief Executive Officer) Sale 7,471 4.05 30,235
2025-01-06 Klee Justin B. (Co-Chief Executive Officer) Sale 7,471 4.04 30,205
2024-12-02 Bedrosian Camille L (Chief Medical Officer) Sale 5,421 5.54 30,005
2024-11-04 Klee Justin B. (Co-Chief Executive Officer) Option Ex 63,690 1.57 99,993
2024-09-30 Mazzariello Gina (Chief Legal Officer) Sale 8,709 3.20 27,842
2024-09-30 Cohen Joshua B (Co-Chief Executive Officer) Sale 18,589 3.20 59,410
2024-09-30 Klee Justin B. (Co-Chief Executive Officer) Sale 18,589 3.20 59,429
2024-09-30 Bedrosian Camille L (Chief Medical Officer) Sale 11,442 3.19 36,557
2024-09-23 Cohen Joshua B (Co-Chief Executive Officer) Option Ex 1,857 1.57 2,915
2024-09-12 Cohen Joshua B (Co-Chief Executive Officer) Option Ex 34,449 1.57 54,084
2024-09-12 Frates James M (Chief Financial Officer) Buy 40,000 2.53 101,359
2024-09-05 Firestone Karen Buy 50,000 2.13 106,600
2024-09-03 Milne George M Jr Buy 100,000 2.20 219,800
2024-05-15 Mazzariello Gina (Chief Legal Officer) Sale 10,455 1.88 19,655
2024-05-15 Quimi Daphne Buy 2,250 1.89 4,252
2024-05-14 Quimi Daphne Buy 2,750 1.89 5,183
2024-03-05 Mazzariello Gina (Chief Legal Officer) Sale 1,540 18.73 28,841
2024-03-05 Cohen Joshua B (Co-Chief Executive Officer) Sale 4,135 18.73 77,440
2024-03-05 Klee Justin B. (Co-Chief Executive Officer) Sale 4,135 18.73 77,440
2024-03-05 Frates James M (Chief Financial Officer) Sale 1,792 18.73 33,560
2024-02-23 Mazzariello Gina (Chief Legal Officer) Sale 2,838 18.76 53,229
2024-01-09 Cohen Joshua B (Co-Chief Executive Officer) Sale 5,841 16.33 95,371
2024-01-09 Klee Justin B. (Co-Chief Executive Officer) Sale 5,841 16.33 95,371
2024-01-09 Yeramian Patrick D (Chief Medical Officer) Sale 2,812 16.33 45,914
2024-01-09 Frates James M (Chief Financial Officer) Sale 2,716 16.33 44,346
2023-12-27 Olinger Margaret (Chief Commercial Officer) Option Ex 25,000 .37 9,250
2023-12-15 Firestone Karen Buy 4,000 14.97 59,880
2023-11-16 Cohen Joshua B (Co-Chief Executive Officer) Option Ex 63,694 1.57 99,999
2023-08-23 Frates James M (Chief Financial Officer) Option Ex 18,165 6.88 124,975
2023-07-12 Olinger Margaret (Chief Commercial Officer) Option Ex 20,000 .37 7,400
2023-05-16 Frates James M (Chief Financial Officer) Sale 32,500 27.26 886,047
2023-05-16 Frates James M (Chief Financial Officer) Option Ex 32,500 6.88 223,600
2023-05-15 Yeramian Patrick D (Chief Medical Officer) Sale 11,965 29.03 347,355
2023-05-15 Yeramian Patrick D (Chief Medical Officer) Option Ex 11,965 3.62 43,373
2023-04-17 Yeramian Patrick D (Chief Medical Officer) Sale 49,579 30.74 1,523,909
2023-04-17 Yeramian Patrick D (Chief Medical Officer) Option Ex 49,579 3.62 179,723
2023-03-29 Morningside Venture Investments Ltd (10% Owner) Sale 29,048 30.45 884,511
2023-03-28 Morningside Venture Investments Ltd (10% Owner) Sale 100,000 30.37 3,037,000
2023-03-27 Morningside Venture Investments Ltd (10% Owner) Sale 60,964 30.52 1,860,926
2023-03-21 Morningside Venture Investments Ltd (10% Owner) Sale 63,448 31.93 2,025,894
2023-03-16 Firestone Karen (Director) Buy 1,000 31.99 31,990
2023-03-16 Cohen Joshua B (Co-Chief Executive Officer) Sale 100,000 32.14 3,214,200
2023-03-16 Klee Justin B. (Co-Chief Executive Officer) Sale 100,000 32.16 3,215,800
2023-03-16 Yeramian Patrick D (Chief Medical Officer) Sale 54,627 32.14 1,755,766
2023-03-16 Frates James M (Chief Financial Officer) Sale 32,500 32.16 1,045,265
2023-03-16 Milne George M Jr (Director) Sale 35,000 32.15 1,125,320
2023-03-15 Morningside Venture Investments Ltd (10% Owner) Sale 150,000 33.40 5,010,000
2023-03-14 Morningside Venture Investments Ltd (10% Owner) Sale 70,714 34.54 2,442,461
2023-03-02 Morningside Venture Investments Ltd (10% Owner) Sale 50,000 33.75 1,687,500
2023-02-24 Mazzariello Gina (Chief Legal Officer) Sale 3,586 34.49 123,670
2023-02-23 Morningside Venture Investments Ltd (10% Owner) Sale 50,000 35.90 1,794,750
2023-02-22 Morningside Venture Investments Ltd (10% Owner) Sale 100,000 35.57 3,557,250
2023-01-06 Olinger Margaret (Chief Commercial Officer) Sale 2,403 36.43 87,550
2023-01-06 Cohen Joshua B (Co-Chief Executive Officer) Sale 5,968 36.43 217,438
2023-01-06 Klee Justin B. (Co-Chief Executive Officer) Sale 5,968 36.43 217,438
2023-01-06 Yeramian Patrick D (Chief Medical Officer) Sale 2,034 36.43 74,106
2023-01-06 Frates James M (Chief Financial Officer) Sale 2,658 36.43 96,841
2022-12-30 Frates James M (Chief Financial Officer) Option Ex 5,000 6.88 34,400
2022-09-09 Dragsa 96 Llc Sale 700,000 30.73 21,514,500
2022-09-08 Dragsa 96 Llc Sale 700,000 29.48 20,636,000
2022-07-06 Als Invest 1 B.v. (10% Owner) Sale 60,609 20.97 1,270,970
2022-05-05 Cohen Joshua B (Co-Chief Executive Officer) Option Ex 334,520 .37 123,772
2022-05-05 Klee Justin B. (Co-Chief Executive Officer) Option Ex 334,520 .37 123,772
2022-01-11 Shabet Rose Sharon Buy 2,300,000 19.00 43,700,000
2022-01-11 Morningside Venture Investments Ltd (10% Owner) Buy 263,158 19.00 5,000,002
2022-01-06 Olinger Margaret (Chief Commercial Officer) Buy 6,842 19.00 129,998
2022-01-06 Cheng Isaac (Director) Buy 6,578 19.00 124,982
2022-01-06 Fonteyne Paul R. (Director) Buy 3,947 19.00 74,993
2022-01-06 Milne George M Jr (Director) Buy 26,315 19.00 499,985

Insider trading activities including stock purchases, stock sales, and option exercises of AMLX listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Amylyx Pharmaceuticals, Inc. (symbol AMLX, CIK number 1658551) see the Securities and Exchange Commission (SEC) website.



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