Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Protagonist Therapeutics, Inc (PTGX) since 2016 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Protagonist Therapeutics, Inc. Table 2 shows the detailed insider transactions. This company's CIK number is 1377121.
Total stock buying since 2016: $35,518,460.
Total stock sales since 2016: $33,213,159.
Total stock option exercises since 2016: $6,879,838.
| Insider Buying | Insider Sales | Option Exercises | ||||
|---|---|---|---|---|---|---|
| Year | Shares | Value | Shares | Value | Shares | Value |
| 2025 | 0 | $0 | 155,590 | $8,274,154 | 110,142 | $1,616,794 |
| 2024 | 0 | $0 | 427,662 | $17,616,801 | 311,171 | $2,786,114 |
| 2023 | 0 | $0 | 1,848 | $30,011 | 32,196 | $178,250 |
| 2022 | 0 | $0 | 0 | $0 | 654,224 | $1,746,272 |
| 2021 | 0 | $0 | 63,025 | $2,009,940 | 63,000 | $231,830 |
| 2020 | 12,000 | $80,400 | 2,499 | $42,952 | 30,843 | $44,902 |
| 2019 | 69,175 | $373,510 | 35,345 | $292,699 | 29,654 | $34,895 |
| 2018 | 0 | $0 | 341,953 | $4,151,278 | 50,064 | $66,748 |
| 2017 | 10,000 | $64,570 | 44,495 | $795,324 | 95,394 | $174,033 |
| 2016 | 2,916,665 | $34,999,980 | 0 | $0 | 0 | $0 |
| Trading Period | Insider Buying | Insider Sales | Option Exercises | |||
|---|---|---|---|---|---|---|
| year-month | Shares | Value | Shares | Value | Shares | Value |
| 2025-08 | 0 | $0 | 4,000 | $237,000 | 0 | $0 |
| 2025-07 | 0 | $0 | 62,859 | $3,450,575 | 0 | $0 |
| 2025-06 | 0 | $0 | 20,000 | $1,125,400 | 20,000 | $160,798 |
| 2025-04 | 0 | $0 | 1,756 | $80,776 | 10,725 | $12,441 |
| 2025-03 | 0 | $0 | 59,417 | $3,380,403 | 79,417 | $1,443,555 |
| 2025-01 | 0 | $0 | 7,558 | $0 | 0 | $0 |
| 2024-11 | 0 | $0 | 256,063 | $11,807,697 | 238,706 | $2,014,611 |
| 2024-09 | 0 | $0 | 22,203 | $992,459 | 20,000 | $291,200 |
| 2024-07 | 0 | $0 | 8,000 | $320,000 | 8,000 | $103,040 |
| 2024-06 | 0 | $0 | 43,000 | $1,511,650 | 8,000 | $103,040 |
| 2024-04 | 0 | $0 | 26,234 | $738,735 | 0 | $0 |
| 2024-03 | 0 | $0 | 57,223 | $1,815,090 | 31,465 | $237,323 |
| 2024-02 | 0 | $0 | 9,939 | $306,170 | 0 | $0 |
| 2024-01 | 0 | $0 | 5,000 | $125,000 | 5,000 | $36,900 |
| 2023-11 | 0 | $0 | 1,848 | $30,011 | 0 | $0 |
| 2023-10 | 0 | $0 | 0 | $0 | 26,000 | $172,860 |
| 2023-04 | 0 | $0 | 0 | $0 | 6,196 | $5,390 |
| 2022-11 | 0 | $0 | 0 | $0 | 502,395 | $1,006,795 |
| 2022-08 | 0 | $0 | 0 | $0 | 20,000 | $84,200 |
| 2022-05 | 0 | $0 | 0 | $0 | 27,742 | $169,353 |
| 2022-04 | 0 | $0 | 0 | $0 | 104,087 | $485,924 |
| 2021-12 | 0 | $0 | 15,000 | $482,175 | 0 | $0 |
| 2021-09 | 0 | $0 | 0 | $0 | 40,000 | $168,400 |
| 2021-08 | 0 | $0 | 14,779 | $702,889 | 10,000 | $8,700 |
| Trade Date | Insider Name | Trade Type | Shares | Price ($) | Value ($) |
|---|---|---|---|---|---|
| 2025-08-27 | Waddill William D. | Sale | 4,000 | 59.25 | 237,000 |
| 2025-07-25 | Patel Dinesh V Ph D (President and CEO) | Sale | 10,415 | 54.78 | 570,533 |
| 2025-07-23 | Patel Dinesh V Ph D (President and CEO) | Sale | 17,520 | 54.79 | 959,920 |
| 2025-07-22 | Patel Dinesh V Ph D (President and CEO) | Sale | 22,065 | 55.05 | 1,214,678 |
| 2025-07-21 | Patel Dinesh V Ph D (President and CEO) | Sale | 12,859 | 54.86 | 705,444 |
| 2025-06-10 | Molina Arturo Md (Chief Medical Officer) | Sale | 10,000 | 57.03 | 570,300 |
| 2025-06-10 | Molina Arturo Md (Chief Medical Officer) | Option Ex | 10,000 | 8.04 | 80,399 |
| 2025-06-09 | Molina Arturo Md (Chief Medical Officer) | Sale | 10,000 | 55.51 | 555,100 |
| 2025-06-09 | Molina Arturo Md (Chief Medical Officer) | Option Ex | 10,000 | 8.04 | 80,399 |
| 2025-04-28 | Selick Harold E | Option Ex | 10,725 | 1.16 | 12,441 |
| 2025-04-22 | Ali Asif (Chief Financial Officer) | Sale | 1,756 | 46.00 | 80,776 |
| 2025-03-17 | Waddill William D. | Sale | 4,000 | 54.25 | 217,000 |
| 2025-03-13 | Molina Arturo Md (Chief Medical Officer) | Sale | 30,514 | 55.74 | 1,700,850 |
| 2025-03-13 | Molina Arturo Md (Chief Medical Officer) | Option Ex | 30,514 | 31.20 | 952,036 |
| 2025-03-12 | Ali Asif (Chief Financial Officer) | Sale | 24,903 | 58.73 | 1,462,553 |
| 2025-03-12 | Ali Asif (Chief Financial Officer) | Option Ex | 24,903 | 15.68 | 390,479 |
| 2025-03-05 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 24,000 | 4.21 | 101,040 |
| 2025-01-16 | Ali Asif (Chief Financial Officer) | Sale | 3,918 | .00 | 0 |
| 2025-01-16 | Molina Arturo Md (Chief Medical Officer) | Sale | 3,640 | .00 | 0 |
| 2024-11-27 | Molina Arturo Md (Chief Medical Officer) | Sale | 26,000 | 44.66 | 1,161,290 |
| 2024-11-27 | Molina Arturo Md (Chief Medical Officer) | Option Ex | 26,000 | 8.04 | 209,039 |
| 2024-11-26 | Gupta Suneel (Chief Development Officer) | Sale | 19,191 | 45.50 | 873,190 |
| 2024-11-26 | Gupta Suneel (Chief Development Officer) | Option Ex | 30,450 | 12.17 | 370,576 |
| 2024-11-26 | Molina Arturo Md (Chief Medical Officer) | Sale | 5,529 | 45.60 | 252,122 |
| 2024-11-26 | Molina Arturo Md (Chief Medical Officer) | Option Ex | 5,529 | 8.04 | 44,453 |
| 2024-11-26 | Patel Dinesh V Ph D (President and CEO) | Sale | 21,480 | 46.25 | 993,450 |
| 2024-11-25 | Gupta Suneel (Chief Development Officer) | Sale | 103,437 | 46.04 | 4,762,239 |
| 2024-11-25 | Gupta Suneel (Chief Development Officer) | Option Ex | 175,000 | 7.73 | 1,353,275 |
| 2024-11-25 | Patel Dinesh V Ph D (President and CEO) | Sale | 78,520 | 46.96 | 3,687,299 |
| 2024-11-25 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 1,727 | 21.58 | 37,268 |
| 2024-11-15 | Molina Arturo Md (Chief Medical Officer) | Sale | 1,906 | 40.98 | 78,107 |
| 2024-09-11 | Ali Asif (Chief Financial Officer) | Sale | 14,203 | 44.53 | 632,459 |
| 2024-09-11 | Ali Asif (Chief Financial Officer) | Option Ex | 12,000 | 15.68 | 188,160 |
| 2024-09-10 | Waddill William D. | Sale | 8,000 | 45.00 | 360,000 |
| 2024-09-10 | Waddill William D. | Option Ex | 8,000 | 12.88 | 103,040 |
| 2024-07-24 | Waddill William D. | Sale | 8,000 | 40.00 | 320,000 |
| 2024-07-24 | Waddill William D. | Option Ex | 8,000 | 12.88 | 103,040 |
| 2024-06-07 | Waddill William D. | Sale | 8,000 | 35.00 | 280,000 |
| 2024-06-07 | Waddill William D. | Option Ex | 8,000 | 12.88 | 103,040 |
| 2024-06-07 | Patel Dinesh V Ph D (President and CEO) | Sale | 35,000 | 35.19 | 1,231,650 |
| 2024-04-18 | Ali Asif (Chief Financial Officer) | Sale | 1,234 | 25.11 | 30,985 |
| 2024-04-01 | Patel Dinesh V Ph D (President and CEO) | Sale | 25,000 | 28.31 | 707,750 |
| 2024-03-07 | Selick Harold E | Option Ex | 6,490 | 1.89 | 12,266 |
| 2024-03-01 | Ali Asif (Chief Financial Officer) | Sale | 14,248 | 32.27 | 459,854 |
| 2024-03-01 | Ali Asif (Chief Financial Officer) | Option Ex | 12,000 | 12.17 | 146,040 |
| 2024-03-01 | Waddill William D. | Sale | 12,975 | 31.34 | 406,636 |
| 2024-03-01 | Waddill William D. | Option Ex | 12,975 | 6.09 | 79,017 |
| 2024-03-01 | Patel Dinesh V Ph D (President and CEO) | Sale | 30,000 | 31.62 | 948,600 |
| 2024-02-29 | Ali Asif (Chief Financial Officer) | Sale | 9,939 | 30.80 | 306,170 |
| 2024-01-09 | Gupta Suneel (Chief Development Officer) | Sale | 5,000 | 25.00 | 125,000 |
| 2024-01-09 | Gupta Suneel (Chief Development Officer) | Option Ex | 5,000 | 7.38 | 36,900 |
| 2023-11-15 | Molina Arturo Md (Chief Medical Officer) | Sale | 1,848 | 16.24 | 30,011 |
| 2023-10-19 | Gupta Suneel (Chief Development Officer) | Option Ex | 20,000 | 7.38 | 147,600 |
| 2023-10-18 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 6,000 | 4.21 | 25,260 |
| 2023-04-10 | Selick Harold E | Option Ex | 6,196 | .87 | 5,390 |
| 2022-11-16 | Liu David Y (Chief R&D Strategy Officer) | Option Ex | 301,437 | 2.00 | 604,077 |
| 2022-08-23 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 20,000 | 4.21 | 84,200 |
| 2022-05-04 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 15,742 | 4.21 | 66,273 |
| 2022-05-03 | Waddill William D. | Option Ex | 12,000 | 8.59 | 103,080 |
| 2022-04-26 | Gupta Suneel (Chief Development Officer) | Option Ex | 40,000 | 7.38 | 295,200 |
| 2022-04-26 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 30,000 | 4.21 | 126,300 |
| 2022-04-14 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 34,087 | 1.89 | 64,424 |
| 2021-12-21 | Patel Dinesh V Ph D (President and CEO) | Sale | 15,000 | 32.15 | 482,175 |
| 2021-09-21 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 40,000 | 4.21 | 168,400 |
| 2021-08-17 | Liu David Y (Chief Scientific Officer) | Sale | 14,779 | 47.56 | 702,889 |
| 2021-08-17 | Liu David Y (Chief Scientific Officer) | Option Ex | 10,000 | .87 | 8,700 |
| 2021-02-11 | Noonberg Sarah B. (Director) | Sale | 3,700 | 25.09 | 92,833 |
| 2021-02-10 | Noonberg Sarah B. (Director) | Sale | 4,700 | 25.73 | 120,931 |
| 2021-01-19 | Patel Dinesh V Ph D (President and CEO) | Sale | 24,846 | 24.60 | 611,112 |
| 2021-01-19 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 13,000 | 4.21 | 54,730 |
| 2020-08-11 | Khosla Chaitan Phd (Director) | Sale | 2,499 | 17.19 | 42,952 |
| 2020-08-11 | Khosla Chaitan Phd (Director) | Option Ex | 2,499 | 1.89 | 4,723 |
| 2020-03-20 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 10,000 | 1.89 | 18,900 |
| 2020-03-12 | Selick Harold E (Director) | Buy | 12,000 | 6.70 | 80,400 |
| 2020-03-12 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 18,344 | 1.16 | 21,279 |
| 2019-12-03 | Kalkofen Donald A. (Chief Financial Officer) | Buy | 1,175 | 5.09 | 5,986 |
| 2019-12-03 | Gupta Suneel (EVP Clinical Operations) | Buy | 30,000 | 5.13 | 153,900 |
| 2019-12-03 | Giraudo Bryan (Director) | Buy | 8,000 | 5.70 | 45,624 |
| 2019-12-03 | Patel Dinesh V Ph D (President and CEO) | Buy | 30,000 | 5.60 | 168,000 |
| 2019-11-26 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 4,000 | 1.16 | 4,640 |
| 2019-08-06 | Liu David Y (Chief Scientific Officer) | Sale | 3,395 | 8.85 | 30,045 |
| 2019-08-06 | Patel Dinesh V Ph D (President and CEO) | Sale | 10,792 | 8.85 | 95,530 |
| 2019-04-01 | Selick Harold E (Director) | Option Ex | 3,310 | 1.31 | 4,336 |
| 2019-03-01 | Liu David Y (Chief Scientific Officer) | Sale | 810 | 8.03 | 6,504 |
| 2019-03-01 | Shames Richard S. (Chief Medical Officer) | Sale | 657 | 8.03 | 5,275 |
| 2019-03-01 | Patel Dinesh V Ph D (President and CEO) | Sale | 2,183 | 8.03 | 17,529 |
| 2019-02-06 | Liu David Y (Chief Scientific Officer) | Sale | 3,821 | 7.74 | 29,563 |
| 2019-02-06 | Shames Richard S. (Chief Medical Officer) | Sale | 2,778 | 7.93 | 22,029 |
| 2019-02-06 | Patel Dinesh V Ph D (President and CEO) | Sale | 10,909 | 7.90 | 86,224 |
| 2019-01-11 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 22,344 | 1.16 | 25,919 |
| 2018-05-17 | Canaan Partners X Llc (10% Owner) | Sale | 38,968 | 6.09 | 237,354 |
| 2018-05-16 | Canaan Partners X Llc (10% Owner) | Sale | 29,441 | 6.46 | 190,071 |
| 2018-05-15 | Canaan Partners X Llc (10% Owner) | Sale | 57,715 | 6.48 | 374,108 |
| 2018-05-14 | Canaan Partners X Llc (10% Owner) | Sale | 77,591 | 6.37 | 494,254 |
| 2018-05-10 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 13,516 | 1.16 | 15,678 |
| 2018-04-02 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 20,000 | 1.16 | 23,200 |
| 2018-03-26 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 11,298 | .87 | 9,829 |
| 2018-03-23 | Canaan Partners X Llc (10% Owner) | Sale | 59,950 | 20.71 | 1,241,324 |
| 2018-03-22 | Canaan Partners X Llc (10% Owner) | Sale | 4,759 | 20.62 | 98,135 |
| 2018-03-21 | Canaan Partners X Llc (10% Owner) | Sale | 17,699 | 20.61 | 364,723 |
| 2018-03-20 | Canaan Partners X Llc (10% Owner) | Sale | 17,060 | 20.61 | 351,538 |
| 2018-03-19 | Canaan Partners X Llc (10% Owner) | Sale | 13,439 | 20.57 | 276,440 |
| 2018-03-16 | Canaan Partners X Llc (10% Owner) | Sale | 6,926 | 20.51 | 142,066 |
| 2018-03-15 | Canaan Partners X Llc (10% Owner) | Sale | 11,751 | 20.64 | 242,517 |
| 2018-03-14 | Canaan Partners X Llc (10% Owner) | Sale | 200 | 20.77 | 4,154 |
| 2018-03-13 | Canaan Partners X Llc (10% Owner) | Sale | 1,204 | 20.84 | 25,093 |
| 2018-03-12 | Liu David Y (Chief Scientific Officer) | Sale | 3,500 | 21.29 | 74,501 |
| 2018-03-12 | Liu David Y (Chief Scientific Officer) | Option Ex | 3,500 | 4.21 | 14,735 |
| 2018-03-02 | Liu David Y (Chief Scientific Officer) | Sale | 875 | 20.00 | 17,500 |
| 2018-03-02 | Liu David Y (Chief Scientific Officer) | Option Ex | 875 | 1.89 | 1,653 |
| 2018-01-16 | Liu David Y (Chief Scientific Officer) | Sale | 875 | 20.00 | 17,500 |
| 2018-01-16 | Liu David Y (Chief Scientific Officer) | Option Ex | 875 | 1.89 | 1,653 |
| 2017-12-22 | Shames Richard S. (Chief Medical Officer) | Sale | 3,529 | 20.50 | 72,344 |
| 2017-12-22 | Shames Richard S. (Chief Medical Officer) | Option Ex | 3,529 | 4.21 | 14,857 |
| 2017-12-21 | Patel Dinesh V Ph D (President and CEO) | Sale | 8,210 | 19.56 | 160,571 |
| 2017-12-21 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 8,210 | 1.89 | 15,516 |
| 2017-12-20 | Patel Dinesh V Ph D (President and CEO) | Sale | 1,790 | 19.55 | 34,987 |
| 2017-12-20 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 1,790 | 1.89 | 3,383 |
| 2017-12-18 | Liu David Y (Chief Scientific Officer) | Sale | 875 | 20.00 | 17,500 |
| 2017-12-18 | Liu David Y (Chief Scientific Officer) | Option Ex | 875 | 1.89 | 1,653 |
| 2017-12-18 | O'neil Thomas P. (Chief Financial Officer) | Sale | 8,000 | 20.00 | 160,000 |
| 2017-12-18 | O'neil Thomas P. (Chief Financial Officer) | Option Ex | 8,000 | 2.69 | 21,480 |
| 2017-11-30 | Liu David Y (Chief Scientific Officer) | Sale | 875 | 20.00 | 17,500 |
| 2017-11-13 | Liu David Y (Chief Scientific Officer) | Sale | 7,000 | 16.97 | 118,762 |
| 2017-11-13 | Liu David Y (Chief Scientific Officer) | Option Ex | 7,000 | 3.05 | 21,350 |
| 2017-10-05 | Shames Richard S. (Chief Medical Officer) | Sale | 2,017 | 19.00 | 38,323 |
| 2017-10-05 | Shames Richard S. (Chief Medical Officer) | Option Ex | 2,017 | 4.21 | 8,491 |
| 2017-09-12 | Shames Richard S. (Chief Medical Officer) | Sale | 3,687 | 14.31 | 52,753 |
| 2017-08-29 | Shames Richard S. (Chief Medical Officer) | Sale | 1,512 | 17.00 | 25,704 |
| 2017-08-29 | Shames Richard S. (Chief Medical Officer) | Option Ex | 1,512 | 4.21 | 6,365 |
| 2017-08-28 | Liu David Y (Chief Scientific Officer) | Sale | 3,500 | 15.00 | 52,500 |
| 2017-08-28 | Liu David Y (Chief Scientific Officer) | Option Ex | 3,500 | 4.21 | 14,735 |
| 2017-07-10 | Liu David Y (Chief Scientific Officer) | Sale | 3,500 | 12.68 | 44,380 |
| 2017-07-10 | Liu David Y (Chief Scientific Officer) | Option Ex | 3,500 | 1.89 | 6,615 |
| 2017-05-16 | Giraudo Bryan (Director) | Buy | 10,000 | 6.46 | 64,570 |
| 2017-05-09 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 19,099 | 1.16 | 22,154 |
| 2017-04-06 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 20,000 | 1.16 | 23,200 |
| 2017-03-10 | Patel Dinesh V Ph D (President and CEO) | Option Ex | 16,362 | .87 | 14,234 |
| 2016-08-16 | Papanek Julie (Director) | Buy | 583,333 | 12.00 | 6,999,996 |
| 2016-08-16 | Canaan Partners X Llc (Director) | Buy | 583,333 | 12.00 | 6,999,996 |
| 2016-08-16 | Shanafelt Armen (Director) | Buy | 583,333 | 12.00 | 6,999,996 |
| 2016-08-16 | Hall Steven Edward (10% Owner) | Buy | 583,333 | 12.00 | 6,999,996 |
| 2016-08-16 | Johnson & Johnson Innovation - Jjdc, Inc. (10% Owner) | Buy | 583,333 | 12.00 | 6,999,996 |
Insider trading activities including stock purchases, stock sales, and option exercises of PTGX listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Protagonist Therapeutics, Inc (symbol PTGX, CIK number 1377121) see the Securities and Exchange Commission (SEC) website.